An Exploratory Study of Telomere Length in the Deep-Sea Shark, Etmopterus granulosus

An Exploratory Study of Telomere Length in the Deep-Sea Shark, Etmopterus granulosus

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The history of elasmobranch ageing highlights the difficulty of age estimation in animals lacking ossified structures.Ageing techniques are numerous, yet all are limited by difficulties of validation and verification and inherent subjectivity.Sample scarcity further hinders progress as limited samples cannot be risked on exploratory techniques.This study explored the use of genetic analysis of telomeres as a method of age determination in a deep-sea shark, Etmopterus granulosus, a representative Minimal residual disease (MRD) detection in solid tumors using circulating tumor DNA: a systematic review of a poorly studied taxon with regard to ageing due to sample scarcity.Telomeres were amplified in 39 individuals with qPCR, compared across samples, and were found to differ across size classes.

More work is needed to determine whether telomeres consistently correlate with size class across elasmobranchs.However, telomeres offer easily obtainable data that can be combined with Discovery and evaluation of active compounds from Xuanfei Baidu formula against COVID-19 via SARS-CoV-2 Mpro traditional methods to provide additional points of comparison for elasmobranch biology.Our results underscore the importance of expanding current ageing methods and highlight a necessary distinction between chronological and biological ages when describing elasmobranch populations.